@kpcross@AndyTeasdale recent regulatory highlight has been very well received by the community. Several discussion threads related to topics raised there.
The Ranitidine worked referenced Searle et all demonstrated that NDMA is formed because of an intermolecular degradation reaction in solid-state. What is fascinating to me is the link between NDMA rate of formation and the crystal morphology, with columnar crystals exhibiting the slowest rate of formation.