thanks a lot Haresh for your information.
I notice that N-nitrosoivacaftor has been added.
I feel that this is similar to N-nitrosoticagrelor case, where a ‘‘false’’ alarm has been set from someone who used a ‘‘fake’’ reference standard and ‘‘identify’’ N-nitrosoticagrelor in the tested sample(s) (unfortunately this ‘‘alarm’’ is still present in the AIs list of EMA).
A relevant discussion has been taken place some time ago in this forum
Apparently someone did not read this 
best regards
Christos