Publication by Kao et al
- A substructure-based screening method employing DataWarrior, an opensource
software, was established to evaluate the risks of NA impurities in drug substances.
- method detected 192 drug substances with a theoretical possibility of NA impurity, 141 of which had not been reported previously.
A substructure-based screening approach to uncover N-nitrosamines.pdf (3.0 MB)