Estimation of Nitrosamines from Nitrites level

[Naiffer_Host]

@desaimayur78 you can check a great example of how the nitrate content in excipients is use to predict theoretically nitrosamine in @schlinjo1975 paper:

How to avoid NDMA in Metformin? (In press)

Back in October 2020, we saw an increased concern about the potential presence of NDMA in Metformin. @trust_user_a @trust_user_b @trust_user_c “As of October 2020, EMA and the national competent authorities are asking marketing authorization holders for metformin-containing medicines to test their medicines before releasing them onto the market,” said EMA’s Committee on Human Medicinal Products (CHMP) in an update to its post-authorization nitrosamine impurity testing procedures” As a Nitros…

@Yosukemino can you refer us to the post you did on the case of GSK?