FDA recalls blood pressure medicine over cancerous chemical

Yosukemino · October 30, 2025, 2:49pm

The recall involves more than 580,000 prazosin hydrochloride capsules distributed by Teva Pharmaceuticals.

N-nitroso Prazosin EP impurity C (CPCA Cat.3)

Eduardo · November 4, 2025, 9:17pm

Thanks for sharing, Yosukemino, it will be interesting to know more about the source of the impurity C. Regards

chrischar · November 5, 2025, 7:13am

Dear Eduardo,

impurity C in the final product could be either from the API itself (as intermediate impurity from its synthetic process) or from the degradation of the API during the stability of the final product (breaking of the amidic bond on the piperazine ring).

Christos