GC-MS/MS & HS-SPME for 14 nitrosamines in 44 pharmaceuticals

Confirmatory Testing & Analytical Challenges
1

Sharing recent publication from the Taiwan FDA team by Chang et al

Monitoring of 14 Nitrosamines in 44 Pharmaceuticals products:

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Tetrazole-ring compound
Alfentanil, Cefazolin, Cefamandole, Cefmenoxime, Cefonicid, Cefoperazone, Cefotetan, Cefotiam, Cefpiramide, Cilostazol, Erythromycin, Tetracycline, Meropenem, Minocycline, Chloramphenicol, Clarithromycin, Azithromycin, Oxytetracycline, Chlortetracycline, Oleandomycin

Antibiotics
Erythromycin, Tetracycline, Meropenem, Minocycline, Chloramphenicol, Clarithromycin, Azithromycin, Oxytetracycline, Chlortetracycline, Oleandomycin

Antihistamines
Diphenhydramine, Carbinoxamine, Chlorpheniramine, Ranitidine, Doxylamine, Dimenhydrinate, Nizatidine

Antipsychotics
Citalopram, Venlafaxine, Escitalopram, Promazine, Chlorpromazine, Doxepin, Amitriptyline, Imipramine, Clomipramine, Chlorprothixene

Others
Benzalkonium chloride, Metformin, Tramadol, Diltiazem, Diethyltoluamide, Mifepristone, Sumatriptan

2 Likes
2

Hi Naiffer,

Can you share full article/literature which was mentioned over here.

Thanks in advance.
MB.

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@Mittalkumar i provided the link. Unfortunately because copyright I can not share the article in here. You can acquire it directly with the publisher.

4

Thanks Naiffer,

Regards,
MB