Limit for Nitroso Atenolol

Hi, @hgajjar.

I think the discussion on N-nitroso-propanolol is helpful to you.

In this thread, the link to an interesting paper was shared by @Diego_HM.
Practical and Science-Based Strategy for Establishing Acceptable Intakes for Drug Product N-Nitrosamine Impurities | Chemical Research in Toxicology (acs.org)

Structural group 5 suggests 440ng/day. However, I am not sure this is acceptable to health authorities.

2 Likes