@Nilesh The WHY of your question is a topic that continues to be controversial and in the center of a lot of regulatory-industry discussions. To me it’s not about the why, but about the WHAT we can do as a community to advance that conversation and build the necessary knowledge to justify the one or the other.
I suggest watching the recording of Dr. Nudelman (@conudel) and Dr. Cross (@kpcross) to dive deep into some of these regulatory approaches. Also curious to hear their opinions on the future of this particular challenge.