I think we can start with fillers as are confirmed to be the largest source of nitrite in the drug products, for example:
*Microcrystalline celloluse
*Crosscarmellose sodium
Moreover, in our experience, also JRS MCC (Vivapur 101 and 102) have a low content of nitrites (<0.2%), even if they didn’t create a specific brand or published their data.
Thanks for sharing DFE white paper.
Unfortunately, we should not rely completely on the risk assessment delivered by the suppliers on taking our decisions. When we made our analysis, we have found significant nitrite content although the risk assessment received from the excipient supplier claims its absence!