Nitrocellulose used in packaging inks and coatings can allow migration of nitrosating agents through the printed layer, which may react with amines present in the product to form nitrosamines.
This raises a question on the suitability of nitrocellulose-based inks in pharmaceutical packaging and the need for safer alternatives such as polyurethane or acrylic binders.
How should packaging materials be evaluated for their potential contribution to nitrosamine formation?