Dear all,
Recently we have find out the nitrosamines impurities in many pharmaceuticals products but I thinking what about pesticides.can nitrosamines only come from medicines it’s also comes from vegetable and fruits.Farmer spray many harmful chemical to growing crops to give more yield.Urea is mostly used in farm and can generate nitroso impurity.
@amol Indeed nitrosamines impurities are known in other categories; however, the focus of our community discussions is in the pharmaceutical space.
N-alkyl nitrosoureas, nitroso carbamates are very well known. But they are activated by a different mechanism than nitrosamines. Also, as the Agencies have not included them in the list, it is a dilemma what to do when you find one in a pharemaceutical.