In nitrosamine impurities cleaning validation, when there are multiple nitrosamine impurities remaining, are the residual limits calculated using their respective AIs? For example, if a product contains NDMA and NDEA, MACO = AI × minimum batch size of the next product / maximum daily dose of the next product, the MACO value of NDMA is calculated using AI = 96ng, and the MACO value of NDEA is calculated using AI = 26.5ng. Do we need to add the limit requirements for total impurity control?