Role of Carbonyl Compounds for N-Nitrosamine Formation during Nitrosation: Kinetics and Mechanisms

New Scientific Knowledge & Development
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Aldehydes catalyze nitrosamine formation reactions even at medium to alkaline pH.
Dr. Pan et al. demonstrated several kinetic simulations of nitrosamine formation with carbonyl compounds in different scenarios in this paper.

https://pubs.acs.org/doi/10.1021/acs.est.3c07461

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Is there any actual case studies available? May be in the form of deficiency from any regulatory authority or any official presentation? Whether any product (DS/DP) has been identified in which the root cause of nitrosamine formation is aldehyde catalyst?