Simple and Practical Method for the Quantitative High-Sensitivity Analysis of N-Nitroso Duloxetine in Duloxetine Drug Products Utilizing LC-MS/MS

Dr. Fukuda et al. from Towa Pharmaceutical Co., Ltd published a literature focusing on the testing method for N-nitroso duloxetine. Using LC-MS/MS they analyzed the trace amounts of NDSRIs by methanol extraction.

You can check the Swissmedic method for Duloxetine. It is similar to Fukuda’s.