Our laboratory recently synthesized a compound suspected to be N-Nitroso Finerenone. Attached are the MSS and HNMR.
Welcome everyone to discuss…
Dear Cato,
if your concern is the validity of the material, the 1H-NMR is a very minor information, specially if presented with no assignment table of the protons.
Usually 2-D NMRs are used in those cases, specially HSQC.
At least, the NMR of the Finerenone should be also shared in order to prove, with the comparison, that the -NH group is not anymore presented on the target molecule.
Furthermore, no MS spectra is identified.
Personally, i consider the synthesis of N-nitrosofinerenone very difficult, as the negative charge of the targeted nitrogen is strongly delocalized due to the resonance with the aromatic ring and the carbonyl moiety of the amide group,
Kind regards
Christos
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