Hi, guys
I want to inform you of the update of the FDA list. In the rev.2, N-nitroso-ciprofloxacin was transferred from the read-across list to the CPCA list. And N-nitroso-atomoxetine was transferred from the CPCA list to the read-across list.
| 2 | N-nitroso-ciprofloxacin | Added to Table 1 | 12/1/2023 |
|---|---|---|---|
| 2 | N-nitroso-ciprofloxacin | Deleted from Table 2 | 12/1/2023 |
| 2 | N-nitroso-atomoxetine | Deleted from Table 1 | 12/1/2023 |
| 2 | N-nitroso-atomoxetine | Added to Table 2 | 12/1/2023 |
N-nitroso-ciprofloxacin: from “Pending” to “Category4 (1500ng/day)”
N-nitroso-atomoxetine: from “Category1 (26.5ng/day)” to “read-across from NNK (100ng/day)”
Please check the details(Updated Information | Recommended Acceptable Intake Limits for Nitrosamine Drug Substance-Related Impurities (NDSRIs) | FDA).