What is CPCA Score for “N-nitroso of 3-Amino-1,2,4-triazole"

[Naiffer_Host]

Thanks, Dinkar. I think this post should help you with the limit definition and justification. The same framework was used to develop CPCA.

Determining recommended acceptable intake limits for N-nitrosamine impurities in pharmaceuticals: Development and application of the Carcinogenic Potency Categorization Approach (CPCA) -Pub

As our community grows, I believe the core understanding of the evolution of the science is critical. This time, I want to bring back to life this publication from June 2024 Determining recommended acceptable intake limits for N-nitrosamine impurities in pharmaceuticals: Development and application of the Carcinogenic Potency Categorization Approach (CPCA) In this publication, the representatives from all the regulatory agencies that constructed the CPCA scoring system, dive deep into how it wa…