A Nitrite Excipient Database: A Useful Tool to Support N-Nitrosamine Risk Assessments for Drug Products

[Naiffer_Host]

With so much attention and discussion around Nitrite content in excipients and the protagonist role in NDSRIs, I wanted to revive a publication from Boetzel et al

A Nitrite Excipient Database: A Useful Tool to Support *N-*Nitrosamine Risk Assessments for Drug Products

A Nitrite Excipient Database - Risk Assessment

If you haven’t, I encourage you to read the recent publication " A Nitrite Excipient Database: A Useful Tool to Support N- Nitrosamine Risk Assessments for Drug Products" by Boetzel et al. A fantastic update on the data-sharing consortium, maintained by Lhasa Limited. The goal of the initiative is to provide a common framework to contextualize and estimate the risk posed by the presence of nitrites to contribute to the formation of nitrosamines in drug products. Key takes aways: Average nitr…

[MarkS]

More than a database or just a tool for risk assessment, but also a community for increasing knowledge around all things nitrite.