N-Nitroso Metformin Chemistry

We are working with N-Nitroso impurity & received the technical justification from impurity supplier that N-Nitrosometformin is not possible to synthesize because due to structural rearrangement & it cannot form at primary amide position it is highly unstable.

Is anybody working on this & can help us to understand the actual chemistry.

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Hi Dileep,
i think that the following thread could answer to your questions

hope it helps,
thanks

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