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New Paper: Impact of antioxidant addition on drug dissolution: Implications for NDSRI mitigation biowaivers
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1
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289
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June 5, 2025
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Comparative DNA damage induced by 8 nitrosamines in primary human and macaque hepatocytes -Pub
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1
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139
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May 27, 2025
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N-nitroso Torasemide Impurity formation and control
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33
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2493
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May 27, 2025
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Optimizing the detection of N-nitrosamine mutagenicity in the Ames test -Pub
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17
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762
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May 23, 2025
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Metformin and nitrosation of guanidines
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8
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479
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May 21, 2025
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Using the relative potency comparison approach, Powley et al have demonstrated the safety of NTTP exposures at or above levels of 1500 ng/day
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2
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373
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May 17, 2025
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Nitrate and nitrite food composition database: an update and extensive deep dive
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2
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322
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May 14, 2025
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HESI GTTC ring trial: Concordance between Ames and rodent carcinogenicity outcomes for N-nitrosamines (NAs) with rat and hamster metabolic conditions -Pub
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0
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122
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May 13, 2025
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NitrosAMIDES - Should they be treated the same as Nitrosamines?
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3
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997
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May 7, 2025
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Understanding Aqueous Nitrosation Kinetics of 4-Substituted Piperidines To Risk Assess Pharmaceutical Processes and Products-Pub
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1
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227
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May 6, 2025
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Interferencia de matriz para cuantificación de NDBA
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0
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82
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May 5, 2025
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🇰🇷 Korea NRA on 'Case Studies on Reducing Impurities in Pharmaceuticals (focusing on NDMA)"
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0
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332
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May 1, 2025
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Industrial Case Studies Demonstrating Applicability of ICH M7Control Options 3 and 4 for Nitrosamine Control -Pub
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4
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729
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April 22, 2025
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Published Article: Tale of Three N-Nitrosamines and the Variables Needed to Assess Their Carcinogenicity In Silico Incorporated into a Single Workflow
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0
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192
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April 22, 2025
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AMES Test Study Designs for Nitrosamine Mutagenicity Testing -Pub
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11
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1393
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April 18, 2025
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N-Nitroso clozapine
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2
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276
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April 3, 2025
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Laboratory Study in Gastric Nitrosamine Formation
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8
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404
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April 2, 2025
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New publication on "Nitrosation" from MultiCASE
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7
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551
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March 29, 2025
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Quantitative Investigation of Nitrosamine Drug Substance-Related Impurities (NDSRIs) Under Artificial Gastric Conditions by Liquid Chromatography–Tandem Mass Spectrometry and Structure–Activity Relationship Analysis -Pub
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0
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306
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March 24, 2025
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📓 Special Issue of OPRD - Analytical Control Strategies for Process Chemists
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0
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216
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February 27, 2025
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Nitrosation and Degradations Reaction Predictions and Limit Calculations
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1
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612
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February 25, 2025
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Impact of Antioxidant Excipients on N-nitrosamine Formation and Bioequivalence in Metformin Formulations - Pub
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3
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718
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February 11, 2025
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Rat Liver Micronucleus Assay as a Nitrosamine Potency Assessment
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1
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214
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January 8, 2025
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Exploration for Chemical Filter Cartridges that Can Reduce Nitrogen Oxides, a Common Factor in the Formation of Nitrosamines
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0
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263
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December 15, 2024
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Requirement after reformulation of existing approved drug product for Europe
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12
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488
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November 12, 2024
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Resolution of Historically Discordant Ames Test Negative / Rodent Carcinogenicity Positive N-nitrosamines using a Sensitive, OECD-aligned Design-Pub
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0
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255
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November 2, 2024
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Nitrosamine Mitigation Case Study
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6
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465
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October 31, 2024
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N-Nitroso Desmethyl Tramadol
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3
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814
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October 29, 2024
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Software for prediction of NDSRI generation
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5
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681
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October 24, 2024
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Bumetanide as a Model NDSRI Substrate: N-nitrosobumetanide impurity formation and its inhibition in bumetanide tablets -Pub
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7
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1218
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October 19, 2024
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