Using the relative potency comparison approach, Powley et al have demonstrated the safety of NTTP exposures at or above levels of 1500 ng/day
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1
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240
|
July 30, 2024
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Nitrosamine Contamination of Pharmaceuticals: Cases in Japan, Formation Mechanisms, Detection Methods, Regulatory Perspectives, and Insights -Pub
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1
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147
|
July 30, 2024
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How to overcome the challenges of manual read-across when assessing nitrosamine acceptable intake limits
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0
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120
|
July 26, 2024
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Leveraging ICH M7 Control Options 3 and 4: Discussion and Clarification Using Industrial Case Studies -Pub
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0
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514
|
July 23, 2024
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Quantum Mechanical Assessment of Nitrosamine Potency -Pub
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3
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412
|
July 15, 2024
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AZIDO Impurities Topic
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4
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1236
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July 11, 2024
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A Case to Support the Continued Use of Rifampin in Clinical Drug–Drug Interaction Studies -Pub
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0
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165
|
July 10, 2024
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Non-mutagenic, carcinogenic impurities
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3
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468
|
June 30, 2024
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Discussion on Cleaning Validation Requirements for Nitrosamines
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3
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903
|
June 24, 2024
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On the role of digital tools in nitrosamine risk assessment for drug substance and drug product manufacturing processes -Pub
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0
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177
|
June 13, 2024
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EMA-funded project to predict in-vivo mutagenicity / mutagenicity classification
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9
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1018
|
June 11, 2024
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Modeling the Impact of Excipients Selection on Nitrosamine Formation towards Risk Mitigation
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16
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3295
|
June 8, 2024
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A new root cause? NOx
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13
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1742
|
November 17, 2023
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Formaldehyde Catalysis of Nitrosamine Formation
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3
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585
|
May 31, 2024
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⚙️🌎CPCA: the gestation, birth, and development -Pub
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5
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1134
|
May 31, 2024
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Genotoxicity assessments of N-nitrosoethylisopropylamine (NEIPA) and N-nitrosodiisopropylamine (NDIPA) in the C57BL/6J mouse -Pub
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0
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276
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May 13, 2024
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Are nitrosamines the connecting link or one of the connecting links between the concepts of phototoxicity and photocarcinogenicity due to the intake of a contaminated medication according to the 2019/ 2023 FDA list?
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41
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1261
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May 11, 2024
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Clinico-pathological correlations after intake of potentially nitrosamine/ NDSRIs contaminated drugs
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1
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287
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April 14, 2024
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Nitrosamines: A new systematic review
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11
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2973
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April 14, 2024
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SOT posters and talks, (shared posters -update)
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3
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794
|
April 10, 2024
|
1st release of Lhasa 'Complex Nitrosamines' data sharing initiative
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6
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1061
|
March 31, 2024
|
Antioxidant as a risk mitigation strategy
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5
|
697
|
March 28, 2024
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Acceptable Intakes (AIs) for 11 Small molecule N-nitrosamines (NAs) -Pub
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17
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2685
|
March 28, 2024
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Lack of effect of antioxidants on Biopharmaceutics Classification System (BCS) Class III drug permeability -Pub
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1
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488
|
March 13, 2024
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Role of Carbonyl Compounds for N-Nitrosamine Formation during Nitrosation: Kinetics and Mechanisms
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0
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393
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March 2, 2024
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In Silico Prediction of Pharmaceutical Degradation Pathways: A Benchmarking Study Using the Software Program Zeneth
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3
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402
|
February 24, 2024
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In Silico Prediction of N-Nitrosamine Formation Pathways of Pharmaceutical Products -Pub
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0
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523
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February 8, 2024
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Metabolic activation of short-chain alkyl N-nitrosamines using Aroclor 1254 or phenobarbital/beta-naphthoflavone-induced rat or hamster S9 – a comparative analysis -Pub
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4
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461
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February 2, 2024
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📚 OPRD Special Issue on Nitrosamines -Pub
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13
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2325
|
January 23, 2024
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N-nitroso Torasemide Impurity formation and control
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23
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1808
|
January 5, 2024
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