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Understanding Aqueous Nitrosation Kinetics of 4-Substituted Piperidines To Risk Assess Pharmaceutical Processes and Products-Pub
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1
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265
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May 6, 2025
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Interferencia de matriz para cuantificación de NDBA
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0
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89
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May 5, 2025
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🇰🇷 Korea NRA on 'Case Studies on Reducing Impurities in Pharmaceuticals (focusing on NDMA)"
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0
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355
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May 1, 2025
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Industrial Case Studies Demonstrating Applicability of ICH M7Control Options 3 and 4 for Nitrosamine Control -Pub
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4
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797
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April 22, 2025
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Published Article: Tale of Three N-Nitrosamines and the Variables Needed to Assess Their Carcinogenicity In Silico Incorporated into a Single Workflow
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0
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202
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April 22, 2025
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N-Nitroso clozapine
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2
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340
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April 3, 2025
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Laboratory Study in Gastric Nitrosamine Formation
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8
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464
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April 2, 2025
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New publication on "Nitrosation" from MultiCASE
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7
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619
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March 29, 2025
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Quantitative Investigation of Nitrosamine Drug Substance-Related Impurities (NDSRIs) Under Artificial Gastric Conditions by Liquid Chromatography–Tandem Mass Spectrometry and Structure–Activity Relationship Analysis -Pub
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0
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326
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March 24, 2025
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📓 Special Issue of OPRD - Analytical Control Strategies for Process Chemists
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0
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231
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February 27, 2025
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Nitrosation and Degradations Reaction Predictions and Limit Calculations
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1
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626
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February 25, 2025
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Impact of Antioxidant Excipients on N-nitrosamine Formation and Bioequivalence in Metformin Formulations - Pub
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3
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797
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February 11, 2025
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Rat Liver Micronucleus Assay as a Nitrosamine Potency Assessment
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1
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227
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January 8, 2025
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Exploration for Chemical Filter Cartridges that Can Reduce Nitrogen Oxides, a Common Factor in the Formation of Nitrosamines
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0
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285
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December 15, 2024
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Requirement after reformulation of existing approved drug product for Europe
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12
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543
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November 12, 2024
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Resolution of Historically Discordant Ames Test Negative / Rodent Carcinogenicity Positive N-nitrosamines using a Sensitive, OECD-aligned Design-Pub
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0
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294
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November 2, 2024
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Nitrosamine Mitigation Case Study
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6
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486
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October 31, 2024
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N-Nitroso Desmethyl Tramadol
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3
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979
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October 29, 2024
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Software for prediction of NDSRI generation
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5
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757
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October 24, 2024
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Bumetanide as a Model NDSRI Substrate: N-nitrosobumetanide impurity formation and its inhibition in bumetanide tablets -Pub
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7
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1272
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October 19, 2024
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Nitrosamine mitigation: NDMA impurity formation and its inhibition in metformin hydrochloride tablets -Pub FDA
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2
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247
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October 15, 2024
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Reactivities of N-Nitrosamines against Common Reagents and Reaction Conditions -Pub
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2
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376
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October 15, 2024
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Selection of Solvent and Positive Control Concentration for Enhanced Ames Test Conditions for N-Nitrosamine Compounds -Pub
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0
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197
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October 11, 2024
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N-Nitrosamines: bacterial mutagenesis and in vitro metabolism -A MUST READ
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9
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844
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October 10, 2024
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Dynamics of Nitroso-STG-19 entering the blood circulation
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1
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141
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October 10, 2024
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Aptar’s N-Sorb Nitrosamine Mitigation Solution Accepted to US FDA’s Emerging Technology Program
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6
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617
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October 2, 2024
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New paper - Use of molar, instead of weight-based, safety limits
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17
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3033
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September 25, 2024
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🙋♂️ Citizen Petition to FDA on Sitagliptin
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21
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3608
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June 7, 2024
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Escaping the cohort of concern: in vitro experimental evidence supports non-mutagenicity of N-nitroso-hydrochlorothiazide -Pub
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1
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270
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September 18, 2024
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Can API with amide should considered a potential candidate for forming nitrosamine impurity
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5
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711
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September 12, 2024
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