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Mitigation of N-Nitrosamine Formation in Ranitidine Hydrochloride by Spray Drying Co-Precipitation with Mannitol, Dextrin, and Antioxidant-Pub
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0
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176
|
June 21, 2025
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Atmospheric Formation of Nitrosamines in Seoul, Korea
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0
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247
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June 9, 2025
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New Paper: Impact of antioxidant addition on drug dissolution: Implications for NDSRI mitigation biowaivers
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1
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339
|
June 5, 2025
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Comparative DNA damage induced by 8 nitrosamines in primary human and macaque hepatocytes -Pub
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1
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169
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May 27, 2025
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N-nitroso Torasemide Impurity formation and control
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33
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3234
|
May 27, 2025
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Optimizing the detection of N-nitrosamine mutagenicity in the Ames test -Pub
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17
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933
|
May 23, 2025
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Metformin and nitrosation of guanidines
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8
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740
|
May 21, 2025
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Using the relative potency comparison approach, Powley et al have demonstrated the safety of NTTP exposures at or above levels of 1500 ng/day
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2
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429
|
May 17, 2025
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Nitrate and nitrite food composition database: an update and extensive deep dive
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2
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456
|
May 14, 2025
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HESI GTTC ring trial: Concordance between Ames and rodent carcinogenicity outcomes for N-nitrosamines (NAs) with rat and hamster metabolic conditions -Pub
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0
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183
|
May 13, 2025
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NitrosAMIDES - Should they be treated the same as Nitrosamines?
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3
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1049
|
May 7, 2025
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Understanding Aqueous Nitrosation Kinetics of 4-Substituted Piperidines To Risk Assess Pharmaceutical Processes and Products-Pub
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1
|
294
|
May 6, 2025
|
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Interferencia de matriz para cuantificación de NDBA
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0
|
92
|
May 5, 2025
|
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🇰🇷 Korea NRA on 'Case Studies on Reducing Impurities in Pharmaceuticals (focusing on NDMA)"
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0
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366
|
May 1, 2025
|
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Industrial Case Studies Demonstrating Applicability of ICH M7Control Options 3 and 4 for Nitrosamine Control -Pub
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4
|
851
|
April 22, 2025
|
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Published Article: Tale of Three N-Nitrosamines and the Variables Needed to Assess Their Carcinogenicity In Silico Incorporated into a Single Workflow
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0
|
210
|
April 22, 2025
|
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N-Nitroso clozapine
|
|
2
|
401
|
April 3, 2025
|
|
Laboratory Study in Gastric Nitrosamine Formation
|
|
8
|
594
|
April 2, 2025
|
|
New publication on "Nitrosation" from MultiCASE
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7
|
696
|
March 29, 2025
|
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Quantitative Investigation of Nitrosamine Drug Substance-Related Impurities (NDSRIs) Under Artificial Gastric Conditions by Liquid Chromatography–Tandem Mass Spectrometry and Structure–Activity Relationship Analysis -Pub
|
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0
|
376
|
March 24, 2025
|
|
📓 Special Issue of OPRD - Analytical Control Strategies for Process Chemists
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|
0
|
241
|
February 27, 2025
|
|
Nitrosation and Degradations Reaction Predictions and Limit Calculations
|
|
1
|
643
|
February 25, 2025
|
|
Impact of Antioxidant Excipients on N-nitrosamine Formation and Bioequivalence in Metformin Formulations - Pub
|
|
3
|
902
|
February 11, 2025
|
|
Rat Liver Micronucleus Assay as a Nitrosamine Potency Assessment
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|
1
|
242
|
January 8, 2025
|
|
Exploration for Chemical Filter Cartridges that Can Reduce Nitrogen Oxides, a Common Factor in the Formation of Nitrosamines
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0
|
302
|
December 15, 2024
|
|
Requirement after reformulation of existing approved drug product for Europe
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12
|
589
|
November 12, 2024
|
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Resolution of Historically Discordant Ames Test Negative / Rodent Carcinogenicity Positive N-nitrosamines using a Sensitive, OECD-aligned Design-Pub
|
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0
|
321
|
November 2, 2024
|
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Nitrosamine Mitigation Case Study
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6
|
514
|
October 31, 2024
|
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N-Nitroso Desmethyl Tramadol
|
|
3
|
1060
|
October 29, 2024
|
|
Software for prediction of NDSRI generation
|
|
5
|
894
|
October 24, 2024
|